A global requirement for the HIR complex in the assembly of chromatin.

Due to its extensive length, DNA is packaged into a protective chromatin structure known as the nucleosome. In order to carry out various cellular functions, nucleosomes must be disassembled, allowing access to the underlying DNA, and subsequently reassembled on completion of these processes. The assembly and disassembly of nucleosomes is dependent on the function of histone modifiers, chromatin remodelers and histone chaperones.
In this review, we discuss the roles of an evolutionarily conserved histone chaperone known as the HIR/HIRA complex. In S. cerevisiae, the HIR complex is made up of the proteins Hir1, Hir2, Hir3 and Hpc2, which collectively act in transcriptional regulation, elongation, gene silencing, cellular senescence and even aging. This review presents an overview of the role of the HIR complex, in yeast as well as other organisms, in each of these processes, in order to give a better understanding of how nucleosome assembly is imperative for cellular homeostasis and genomic integrity. This article is part of a Special Issue entitled: Histone chaperones and Chromatin assembly.

Nucleosome assembly factors CAF-1 and HIR modulate epigenetic switching frequencies in an H3K56 acetylation-associated manner in Candida albicans.

CAF-1 and HIR are highly conserved histone chaperone protein complexes that function in the assembly of nucleosomes onto chromatin. CAF-1 is characterized as having replication-coupled nucleosome activity, whereas the HIR complex can assemble nucleosomes independent of replication. Histone H3K56 acetylation, controlled by the acetyltransferase Rtt109 and deacetylase Hst3, also plays a significant role in nucleosome assembly. In this study, we generated a set of deletion mutants to genetically characterize pathway-specific and overlapping functions of CAF-1 and HIR in C. albicans. Their roles in epigenetic maintenance of cell type were examined by using the white-opaque switching system in C. albicans.
 A global requirement for the HIR complex in the assembly of chromatin.
We show that CAF-1 and HIR play conserved roles in UV radiation recovery, repression of histone gene expression, correct chromosome segregation, and stress responses. Unique to C. albicans, the cac2Δ/Δ mutant shows increased sensitivity to the Hst3 inhibitor nicotinamide, while the rtt109Δ/Δ cac2Δ/Δ and hir1Δ/Δ cac2Δ/Δ mutants are resistant to nicotinamide.
CAF-1 plays a major role in maintaining cell types, as the cac2Δ/Δ mutant exhibited increased switching frequencies in both directions and switched at a high frequency to opaque in response to nicotinamide. Like the rtt109Δ/Δ mutant, the hir1Δ/Δ cac2Δ/Δ double mutant is defective in maintaining the opaque cell fate and blocks nicotinamide-induced opaque formation, and the defects are suppressed by ectopic expression of the master white-opaque regulator Wor1. Our data suggest an overlapping function of CAF-1 and HIR in epigenetic regulation of cell fate determination in an H3K56 acetylation-associated manner.

Visible infrared spin-scan radiometer atmospheric sounder radiometric calibration: an inflight evaluation from intercomparisons with HIRS and radiosonde measurements.

The Visible IR spin-scan radiometer Atmospheric Sounder (VAS) is the first sounding instrument placed in geostationary orbit. The calibration procedure for determining VAS radiances requires modeling the contributions of the telescope foreoptics components to the background radiation. A simple relation between target radiance and detector output voltage is derived.
The calibration procedure is successfully tested by comparisons with HIRS and radiosonde data. After removing a negative offset of up to 3 degrees C in three of the upper atmospheric CO(2) bands of VAS, the capability to produce accurate soundings (within 2 degrees C of radiosonde) was demonstrated.

The mitotic Clb cyclins are required to alleviate HIR-mediated repression of the yeast histone genes at the G1/S transition.

The histone genes are an important group of cell cycle regulated genes whose transcription is activated during the G1/S transition and repressed in early G1, late S, and G2/M. The HIR complex, comprised of Hir1, Hir2, Hir3 and Hpc2, regulates three of the four histone gene loci. While relief of repression at the G1/S boundary involves the HIR complex, as well as other cofactors, the mechanism by which this derepression occurs remains unknown. To better understand how transcriptional repression contributes to periodic expression in the cell cycle, we sought to identify the cell cycle signals required to alleviate HIR-mediated repression of the histone genes.

NA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV735845 1.0 ug DNA Ask for price

NP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV814299 1.0 ug DNA
EUR 540

CS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709011 1.0 ug DNA
EUR 379.2

HP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703719 1.0 ug DNA
EUR 540

C5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704421 1.0 ug DNA
EUR 540

S7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747677 1.0 ug DNA Ask for price

IV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730175 1.0 ug DNA Ask for price

NM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736283 1.0 ug DNA Ask for price

XM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756071 1.0 ug DNA Ask for price

XS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756089 1.0 ug DNA Ask for price

MAA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732365 1.0 ug DNA Ask for price

MCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732641 1.0 ug DNA Ask for price

MEB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732671 1.0 ug DNA Ask for price

mF4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732743 1.0 ug DNA Ask for price

GCY Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV726557 1.0 ug DNA Ask for price

FND Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV725471 1.0 ug DNA Ask for price

ST2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749651 1.0 ug DNA
EUR 686.4

ST3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749657 1.0 ug DNA Ask for price

ST4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749669 1.0 ug DNA Ask for price

ST8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV749687 1.0 ug DNA Ask for price

TDD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750293 1.0 ug DNA Ask for price

THM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750401 1.0 ug DNA Ask for price

DM1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723179 1.0 ug DNA Ask for price

DWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723515 1.0 ug DNA Ask for price

EBM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723683 1.0 ug DNA Ask for price

EGI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV723929 1.0 ug DNA Ask for price

F7R Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV724757 1.0 ug DNA Ask for price

MLS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733631 1.0 ug DNA Ask for price

MOK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733685 1.0 ug DNA Ask for price

MPE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV733739 1.0 ug DNA Ask for price

MSD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV734285 1.0 ug DNA Ask for price

CPP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759281 1.0 ug DNA
EUR 2148

CPQ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV759287 1.0 ug DNA
EUR 686.4

TOC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV750677 1.0 ug DNA Ask for price

PB1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV815385 1.0 ug DNA
EUR 540

UTX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV814419 1.0 ug DNA
EUR 540

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707157 1.0 ug DNA
EUR 379.2

AEN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707163 1.0 ug DNA
EUR 379.2

AGK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707187 1.0 ug DNA
EUR 379.2

ALB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707271 1.0 ug DNA
EUR 379.2

ANG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707325 1.0 ug DNA
EUR 379.2

ATM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707655 1.0 ug DNA
EUR 379.2

BID Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707847 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707871 1.0 ug DNA
EUR 379.2

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV707877 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708255 1.0 ug DNA
EUR 379.2

CA8 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708261 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708339 1.0 ug DNA
EUR 379.2

CBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708345 1.0 ug DNA
EUR 379.2

CGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708669 1.0 ug DNA
EUR 379.2

CKB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708753 1.0 ug DNA
EUR 379.2

CRK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708987 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708993 1.0 ug DNA
EUR 379.2

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV708999 1.0 ug DNA
EUR 379.2

DTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709467 1.0 ug DNA
EUR 379.2

EVL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV709839 1.0 ug DNA
EUR 379.2

PIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713469 1.0 ug DNA
EUR 379.2

PTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713985 1.0 ug DNA
EUR 379.2

RGR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV714303 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715317 1.0 ug DNA
EUR 379.2

Sp2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715323 1.0 ug DNA
EUR 379.2

Syk Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715605 1.0 ug DNA
EUR 379.2

TK1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV715875 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710247 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710253 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710259 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710265 1.0 ug DNA
EUR 379.2

FTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710271 1.0 ug DNA
EUR 379.2

FUZ Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710289 1.0 ug DNA
EUR 379.2

GIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710403 1.0 ug DNA
EUR 379.2

GRN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710661 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710829 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV710835 1.0 ug DNA
EUR 379.2

HYI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711141 1.0 ug DNA
EUR 379.2

JTB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711555 1.0 ug DNA
EUR 379.2

LBH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV711897 1.0 ug DNA
EUR 379.2

LTF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712071 1.0 ug DNA
EUR 379.2

LUM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712083 1.0 ug DNA
EUR 379.2

LXN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712089 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712167 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712173 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712179 1.0 ug DNA
EUR 379.2

MAX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712185 1.0 ug DNA
EUR 379.2

MPI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712365 1.0 ug DNA
EUR 379.2

HGF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV701979 1.0 ug DNA
EUR 540

CRP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703479 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703695 1.0 ug DNA
EUR 540

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV703815 1.0 ug DNA
EUR 540

FGA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704103 1.0 ug DNA
EUR 540

NNT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV704253 1.0 ug DNA
EUR 379.2

LY9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705291 1.0 ug DNA
EUR 540

DUT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705459 1.0 ug DNA
EUR 540

NPL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705585 1.0 ug DNA
EUR 540

BMF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705639 1.0 ug DNA
EUR 540

FTO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV705999 1.0 ug DNA
EUR 540

MIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV706503 1.0 ug DNA
EUR 540

C8A Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702501 1.0 ug DNA
EUR 540

SLN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV702969 1.0 ug DNA
EUR 540

TTK Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716385 1.0 ug DNA
EUR 379.2

UBB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716529 1.0 ug DNA
EUR 379.2

WAC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV716727 1.0 ug DNA
EUR 379.2

AFA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718313 1.0 ug DNA Ask for price

AIC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718391 1.0 ug DNA Ask for price

AOM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV718865 1.0 ug DNA Ask for price

ATD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV719171 1.0 ug DNA Ask for price

NF2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712731 1.0 ug DNA
EUR 379.2

NMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712773 1.0 ug DNA
EUR 379.2

OAT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV712983 1.0 ug DNA
EUR 379.2

OS9 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV713019 1.0 ug DNA
EUR 379.2

CCT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720665 1.0 ug DNA Ask for price

CCV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV720719 1.0 ug DNA Ask for price

CHR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721169 1.0 ug DNA Ask for price

CMM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721403 1.0 ug DNA Ask for price

CNC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721451 1.0 ug DNA Ask for price

COP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721595 1.0 ug DNA Ask for price

CRG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721781 1.0 ug DNA Ask for price

CRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721793 1.0 ug DNA Ask for price

CSE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721835 1.0 ug DNA Ask for price

CTD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV721919 1.0 ug DNA Ask for price

DCE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722333 1.0 ug DNA Ask for price

DDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV722357 1.0 ug DNA Ask for price

RP6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747185 1.0 ug DNA Ask for price

RSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747629 1.0 ug DNA Ask for price

S11 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747683 1.0 ug DNA Ask for price

S12 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV747689 1.0 ug DNA Ask for price

SDU Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV748127 1.0 ug DNA Ask for price

SEA Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV748133 1.0 ug DNA Ask for price

RET Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792597 1.0 ug DNA
EUR 379.2

SFN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792783 1.0 ug DNA
EUR 379.2

TKT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV807481 1.0 ug DNA
EUR 379.2

TKT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV807487 1.0 ug DNA
EUR 379.2

DCI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV809319 1.0 ug DNA
EUR 379.2

PB1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811119 1.0 ug DNA
EUR 379.2

GBL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811197 1.0 ug DNA
EUR 379.2

NMB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV792189 1.0 ug DNA
EUR 379.2

NLP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV811935 1.0 ug DNA
EUR 379.2

DCI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812301 1.0 ug DNA
EUR 379.2

RIP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812619 1.0 ug DNA
EUR 379.2

HNT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV812739 1.0 ug DNA
EUR 379.2

GAS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV813447 1.0 ug DNA
EUR 379.2

PDR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739871 1.0 ug DNA Ask for price

PIH Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV740315 1.0 ug DNA Ask for price

PRD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV741569 1.0 ug DNA Ask for price

PRS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV741749 1.0 ug DNA Ask for price

JBS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730193 1.0 ug DNA Ask for price

JPD Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730199 1.0 ug DNA Ask for price

KFM Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730349 1.0 ug DNA Ask for price

KMS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730469 1.0 ug DNA Ask for price

KSS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730745 1.0 ug DNA Ask for price

KWE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730751 1.0 ug DNA Ask for price

LCO Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV730883 1.0 ug DNA Ask for price

GTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV727145 1.0 ug DNA Ask for price

HMI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728375 1.0 ug DNA Ask for price

HPT Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728723 1.0 ug DNA Ask for price

HTL Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV728969 1.0 ug DNA Ask for price

NSX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736493 1.0 ug DNA Ask for price

NT3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736499 1.0 ug DNA Ask for price

OAP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736655 1.0 ug DNA Ask for price

OED Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV736703 1.0 ug DNA Ask for price

TYS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV754913 1.0 ug DNA Ask for price

VCF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755573 1.0 ug DNA Ask for price

VDI Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755609 1.0 ug DNA Ask for price

WSN Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755987 1.0 ug DNA Ask for price

WT2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755993 1.0 ug DNA Ask for price

WTS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV755999 1.0 ug DNA Ask for price

WWS Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756017 1.0 ug DNA Ask for price

XCE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756041 1.0 ug DNA Ask for price

XGR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756047 1.0 ug DNA Ask for price

XIC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV756059 1.0 ug DNA Ask for price

FTX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV761753 1.0 ug DNA
EUR 1104

Rnr1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV746051 1.0 ug DNA Ask for price

Rnr2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV746057 1.0 ug DNA Ask for price

Rnr3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV746063 1.0 ug DNA Ask for price

RNR4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV746069 1.0 ug DNA Ask for price

RNR5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV746075 1.0 ug DNA Ask for price

PYY3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV742199 1.0 ug DNA Ask for price

RCA1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV742625 1.0 ug DNA Ask for price

RCD1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV742679 1.0 ug DNA Ask for price

RMD1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV742835 1.0 ug DNA Ask for price

PABX Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739553 1.0 ug DNA Ask for price

PABY Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739559 1.0 ug DNA Ask for price

PBG1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739649 1.0 ug DNA Ask for price

PCAP Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV739655 1.0 ug DNA Ask for price

LIPB Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732161 1.0 ug DNA Ask for price

MBS1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732569 1.0 ug DNA Ask for price

MBS2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732575 1.0 ug DNA Ask for price

MBS3 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732581 1.0 ug DNA Ask for price

MDRV Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732659 1.0 ug DNA Ask for price

MER5 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732725 1.0 ug DNA Ask for price

MGC1 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732761 1.0 ug DNA Ask for price

MHAC Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732767 1.0 ug DNA Ask for price

MHS2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732773 1.0 ug DNA Ask for price

MHS4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732779 1.0 ug DNA Ask for price

MHS6 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732785 1.0 ug DNA Ask for price

MIC7 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732791 1.0 ug DNA Ask for price

MICF Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732803 1.0 ug DNA Ask for price

MICG Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV732809 1.0 ug DNA Ask for price

FUSE Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV726395 1.0 ug DNA Ask for price

G6PR Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

LV726419 1.0 ug DNA Ask for price
By measuring histone gene transcription in strains with various combinations of clb mutations, we found that the mitotic Clb1/Clb2 cyclins are required to alleviate Hir-mediated repression during the G1/S transition and that Clb2 physically interacts with the HIR complex. While the HIR complex regulates histone gene transcription in combination with two other histone H3/H4 chaperones, Asf1 and Rtt106, our data demonstrate that the mitotic Clb cyclins are necessary to specifically alleviate the repressive action of the HIR complex itself in order to allow proper expression of the histone genes in late G1/early S phase.

Leave a Reply

Your email address will not be published.