Overlapping regulation of CenH3 localization and histone H3 turnover by CAF-1 and HIR proteins in Saccharomyces cerevisiae.

Correct chromosome segregation relies on the centromere-specific histone H3 isoform identified usually as CenH3, or as Cse4 in budding yeast. Cytological experiments have proven that Cse4 seems at extracentromeric loci in yeast cells poor for each the CAF-1 and HIR histone H3/H4 deposition complexes, per elevated nondisjunction in these double mutant cells. Right here, we examined molecular features of this Cse4 mislocalization. Genome-scale chromatin immunoprecipitation analyses demonstrated broader distribution of Cse4 exterior of centromeres in cac1Δ hir1Δ double mutant cells that lack each CAF-1 and HIR complexes than in both single mutant.
Nonetheless, cytological localization confirmed that the important inside kinetochore element Mif2 (CENP-C) was not recruited to extracentromeric Cse4 in cac1Δ hir1Δ double mutant cells. We additionally noticed that rpb1-1 mutants displayed a modestly elevated Cse4 half-life at nonpermissive temperatures, suggesting that turnover of Cse4 is partially depending on Pol II transcription. We used genome-scale assays to exhibit that the CAF-1 and HIR complexes independently stimulate replication-independent histone H3 turnover charges. We talk about methods through which altered histone change kinetics might have an effect on eviction of Cse4 from noncentromeric loci.

The leucine-rich repeat (LRR) protein, CaLRR1, interacts with the hypersensitive induced response (<em>HIR</em>) protein, Ca<em>HIR</em>1, and suppresses cell demise induced by the Ca<em>HIR</em>1 protein.

Leucine-rich repeat proteins (LRRs) operate in a lot of sign transduction pathways by way of protein-protein interactions. The gene encoding a small protein of pepper, CaLRR1, is particularly induced upon pathogen problem and therapy with pathogen-associated molecular patterns (PAMPs). We recognized a pepper hypersensitive induced response (CaHIR1) protein that interacts with the LRR area of the CaLRR1 protein utilizing yeast two-hybrid screening. Ectopic expression of the pepper CaHIR1 gene induces cell demise in tobacco and Arabidopsis, indicating that the CaHIR1 protein could also be a constructive regulator of HR-like cell demise.
 Overlapping regulation of CenH3 localization and histone H3 turnover by CAF-1 and HIR proteins in Saccharomyces cerevisiae.
As a result of transformation may be very troublesome in pepper vegetation, we over-expressed CaLRR1 and CaHIR1 in Arabidopsis to find out mobile capabilities of the 2 genes. The over-expression of the CaHIR1 gene, however not the CaLRR1 gene, in transgenic Arabidopsis confers illness resistance in response to Pseudomonas syringae an infection, accompanied by the sturdy expression of PR genes, the buildup of each salicylic acid and H(2)O(2), and Okay(+) efflux in plant cells.
In Arabidopsis and tobacco vegetation over-expressing each CaHIR1 and CaLRR1, the CaLRR1 protein suppresses not solely CaHIR1-induced cell demise, but in addition PR gene expression elicited by CaHIR1 by way of its affiliation with HIR protein. We suggest that the CaLRR1 protein capabilities as a novel damaging regulator of CaHIR1-mediated cell demise responses in vegetation.

FIP2 and Rip11 specify Rab11a-mediated mobile distribution of GLUT4 and FAT/CD36 in H9c2-hIR cells.

Rab11a has been proven to be concerned in numerous vesicle trafficking processes. To additional outline the purposeful position of Rab11a in vesicle motion we knocked down gene expression of Rab11a and two of its effectors, Rip11 and FIP2, in H9c2-hIR cells and measured the cell floor abundance of GLUT4myc and FAT/CD36. We noticed that by flattening Rab11a, each GLUT4myc and FAT/CD36 abundance on the plasma membrane had been considerably elevated. Within the case of GLUT4myc, the in vitro knockdown of FIP2 additionally elevated the cell floor abundance of GLUT4myc.
Knockdown of each FIP2 and Rip11 improve the abundance of FAT/CD36 on the plasma membrane. Stimulated translocation of GLUT4myc and FAT/CD36 is just not altered after gene knockdown of Rab11a. These knowledge subsequently present that (i) Rab11a regulates cell floor abundance of each GLUT4 and FAT/CD36 and that (ii) each Rab11a-dependent processes are in another way regulated by Rab11a effector proteins.

Replication-independent histone deposition by the HIR advanced and Asf1.

The orderly deposition of histones onto DNA is mediated by conserved meeting complexes, together with chromatin meeting factor-1 (CAF-1) and the Hir proteins . CAF-1 and the Hir proteins function in distinct however functionally overlapping histone deposition pathways in vivo . The Hir proteins and CAF-1 share a typical associate, the extremely conserved histone H3/H4 binding protein Asf1, which binds the center subunit of CAF-1 in addition to to Hir proteins . Asf1 binds to newly synthesized histones H3/H4 , and this advanced stimulates histone deposition by CAF-1 .

HIRIP3 Antibody

E305092 100ug/200ul
EUR 275
Description: Available in various conjugation types.

HIRIP3 antibody

70R-17741 50 ul
EUR 289
Description: Rabbit polyclonal HIRIP3 antibody

HIRIP3 antibody

70R-2185 50 ug
EUR 467
Description: Rabbit polyclonal HIRIP3 antibody raised against the middle region of HIRIP3

HIRIP3 Antibody

GWB-MV194E 50ug Ask for price

anti- HIRIP3 antibody

FNab03871 100µg
EUR 702
Description: Antibody raised against HIRIP3

Polyclonal HIRIP3 Antibody

APR02968G 0.05ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIRIP3 . This antibody is tested and proven to work in the following applications:

HIRIP3 Polyclonal Antibody

30792 100ul
EUR 439

HIRIP3 Polyclonal Antibody

30792-100ul 100ul
EUR 302.4

HIRIP3 Polyclonal Antibody

30792-50ul 50ul
EUR 224.4

HIRIP3 Polyclonal Antibody

E-AB-18848-120uL 120uL
EUR 240
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-18848-200uL 200uL
EUR 399
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-18848-20uL 20uL
EUR 73
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-18848-60uL 60uL
EUR 143
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-61469-120uL 120uL
EUR 320
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-61469-200uL 200uL
EUR 530
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-61469-60uL 60uL
EUR 200
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-61469-each each Ask for price
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-52761-120uL 120uL
EUR 240
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-52761-200uL 200uL
EUR 399
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-52761-20uL 20uL
EUR 73
Description: Unconjugated

HIRIP3 Polyclonal Antibody

E-AB-52761-60uL 60uL
EUR 143
Description: Unconjugated

OAAN03627-50UL - HIRIP3 Antibody

OAAN03627-50UL 50ul
EUR 149

Polyclonal HIRIP3 Antibody (Center)

APR16639G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human HIRIP3 (Center). This antibody is tested and proven to work in the following applications:

OAAN03627-100UL - HIRIP3 Antibody

OAAN03627-100UL 100ul
EUR 249

OAAN03627-200UL - HIRIP3 Antibody

OAAN03627-200UL 200ul
EUR 389

HIRIP3 Rabbit Polyclonal Antibody

E10G32013 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

HIRIP3 Rabbit Polyclonal Antibody

E10G09929 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

HIRIP3 Rabbit Polyclonal Antibody

E10G02926 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

HIRIP3 Polyclonal Conjugated Antibody

C30792 100ul
EUR 476.4

HIRIP3 Polyclonal Conjugated Antibody

C31854 100ul
EUR 476.4

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx037953-100ug 100 ug
EUR 469.2

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx233871-100ug 100 ug
EUR 661.2

HIRA-Interacting Protein 3 (HIRIP3) Antibody

20-abx113016
  • Ask for price
  • Ask for price
  • 150 ul
  • 50 ul

HIRA-Interacting Protein 3 (HIRIP3) Antibody

20-abx005315
  • Ask for price
  • Ask for price
  • Ask for price
  • Ask for price
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx030421-400ul 400 ul
EUR 627.6

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx030421-80l 80 µl
EUR 343.2

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx005315-100l 100 µl
EUR 400

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx005315-20l 20 µl
EUR 175

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx005315-50l 50 µl
EUR 275

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx037953-100g 100 µg
EUR 337.5

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx113016-100l 100 µl
EUR 612.5

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx233871-100g 100 µg
EUR 350

HIRA-Interacting Protein 3 (HIRIP3) Antibody

abx030421-400l 400 µl
EUR 518.75

HIRIP3

CSB-CL883612HU 10 μg plasmid + 200μl Glycerol Ask for price

ARP58286_P050-25UL - HIRIP3 Antibody - middle region

ARP58286_P050-25UL 25ul
EUR 99

ARP58286_P050 - HIRIP3 antibody - middle region (ARP58286_P050)

ARP58286_P050 100ul
EUR 389

HIRIP3 siRNA

20-abx919397
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

HIRIP3 siRNA

20-abx919398
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

HIRIP3 (untagged)-Human HIRA interacting protein 3 (HIRIP3)

SC324592 10 µg Ask for price

HIRIP3 (untagged)-Human HIRA interacting protein 3 (HIRIP3)

SC117881 10 µg Ask for price

Hirip3 (GFP-tagged) - Mouse HIRA interacting protein 3 (Hirip3)

MG209311 10 µg Ask for price

HIRIP3 (GFP-tagged) - Human HIRA interacting protein 3 (HIRIP3)

RG200510 10 µg Ask for price

Hirip3 (untagged) - Mouse HIRA interacting protein 3 (Hirip3), (10ug)

MC219487 10 µg Ask for price

HIRIP3 Rabbit pAb

E2507014 100ul
EUR 225
Description: Available in various conjugation types.

HIRIP3 Rabbit pAb

A7014-100ul 100 ul
EUR 369.6

HIRIP3 Rabbit pAb

A7014-200ul 200 ul
EUR 550.8

HIRIP3 Rabbit pAb

A7014-20ul 20 ul
EUR 219.6

HIRIP3 Rabbit pAb

A7014-50ul 50 ul
EUR 267.6

HIRIP3 (Myc-DDK-tagged)-Human HIRA interacting protein 3 (HIRIP3)

RC200510 10 µg Ask for price

Hirip3 (Myc-DDK-tagged) - Mouse HIRA interacting protein 3 (Hirip3)

MR209311 10 µg Ask for price

HIRIP3 cloning plasmid

CSB-CL883612HU-10ug 10ug
EUR 451.2
Description: A cloning plasmid for the HIRIP3 gene.

Hirip3 (untagged ORF) - Rat HIRA interacting protein 3 (Hirip3), (10 ug)

RN200696 10 µg Ask for price

HIRIP3 Blocking Peptide

33R-8235 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of HIRIP3 antibody, catalog no. 70R-2185

HIRIP3 ELISA KIT|Human

EF010125 96 Tests
EUR 826.8

HIRIP3 (Center) Rabbit pAb

E2613959 100ul
EUR 225
Description: Available in various conjugation types.

Human HIRIP3 shRNA Plasmid

20-abx955558
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Mouse HIRIP3 shRNA Plasmid

20-abx982088
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

Hirip3 (Myc-DDK-tagged ORF) - Rat HIRA interacting protein 3 (Hirip3), (10 ug)

RR200696 10 µg Ask for price

Lenti ORF clone of Hirip3 (mGFP-tagged) - Mouse HIRA interacting protein 3 (Hirip3)

MR209311L4 10 µg Ask for price

HIRIP3 (untagged) - Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 2

SC331200 10 µg Ask for price

HIRIP3 Recombinant Protein (Rat)

RP204605 100 ug Ask for price

Hirip3 ORF Vector (Rat) (pORF)

ORF068203 1.0 ug DNA
EUR 607.2

HIRIP3 Recombinant Protein (Mouse)

RP141530 100 ug Ask for price

HIRIP3 Recombinant Protein (Human)

RP014686 100 ug Ask for price

HIRIP3 (GFP-tagged) - Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 2

RG233362 10 µg Ask for price

HIRIP3 ORF Vector (Human) (pORF)

ORF004896 1.0 ug DNA
EUR 114

Hirip3 ORF Vector (Mouse) (pORF)

ORF047178 1.0 ug DNA
EUR 607.2

Lenti ORF clone of Hirip3 (Myc-DDK-tagged) - Mouse HIRA interacting protein 3 (Hirip3)

MR209311L3 10 µg Ask for price

Human HIRIP3 knockout cell line

ABC-KH6764 1 vial Ask for price
Description: Human HIRIP3 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human HIRIP3 knockdown cell line

ABC-KD6764 1 vial Ask for price
Description: Human HIRIP3 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human HIRIP3 Protein Lysate 20ug

IHUHIRIP3PLLY20UG each
EUR 213
Description: Human HIRIP3 Protein Lysate 20ug

HIRIP3 (Myc-DDK tagged) - Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 2

RC233362 10 µg Ask for price

Lenti ORF clone of Hirip3 (mGFP-tagged ORF) - Rat HIRA interacting protein 3 (Hirip3), (10 ug)

RR200696L4 10 µg Ask for price

Lenti ORF particles, Hirip3 (GFP-tagged) - Mouse HIRA interacting protein 3 (Hirip3), 200ul, >10^7 TU/mL

MR209311L4V 200 µl Ask for price

Lenti ORF particles, HIRIP3 (mGFP-tagged) - Human HIRA interacting protein 3 (HIRIP3), 200ul, >10^7 TU/mL

RC200510L4V 200 µl Ask for price

Lenti ORF clone of Hirip3 (Myc-DDK-tagged ORF) - Rat HIRA interacting protein 3 (Hirip3), (10 ug)

RR200696L3 10 µg Ask for price

OCOA13525-20UG - HIRIP3 Protein Lysate

OCOA13525-20UG 20ug
EUR 169

Lenti ORF particles, Hirip3 (GFP-tagged ORF) - Rat HIRA interacting protein 3 (Hirip3), 200ul, >10^7 TU/mL

RR200696L4V 200 µl Ask for price

Lenti ORF particles, HIRIP3 (Myc-DDK tagged) - Human HIRA interacting protein 3 (HIRIP3), 200ul, >10^7 TU/mL

RC200510L3V 200 µl Ask for price

Lenti ORF particles, Hirip3 (Myc-DDK-tagged) - Mouse HIRA interacting protein 3 (Hirip3), 200ul, >10^7 TU/mL

MR209311L3V 200 µl Ask for price

Lenti ORF particles, Hirip3 (Myc-DDK-tagged ORF) - Rat HIRA interacting protein 3 (Hirip3), 200ul, >10^7 TU/mL

RR200696L3V 200 µl Ask for price

HIRIP3 3'UTR GFP Stable Cell Line

TU059797 1.0 ml
EUR 1672.8

Hirip3 3'UTR GFP Stable Cell Line

TU159519 1.0 ml Ask for price

Hirip3 3'UTR GFP Stable Cell Line

TU255784 1.0 ml Ask for price

Hirip3 sgRNA CRISPR Lentivector set (Rat)

K7156001 3 x 1.0 ug
EUR 406.8

HIRIP3 sgRNA CRISPR Lentivector set (Human)

K0953201 3 x 1.0 ug
EUR 406.8

Hirip3 sgRNA CRISPR Lentivector set (Mouse)

K4629701 3 x 1.0 ug
EUR 406.8

HIRIP3 Protein Vector (Rat) (pPM-C-HA)

PV272812 500 ng
EUR 723.6

HIRIP3 Protein Vector (Rat) (pPB-C-His)

PV272810 500 ng
EUR 723.6

HIRIP3 Protein Vector (Rat) (pPB-N-His)

PV272811 500 ng
EUR 723.6

HIRIP3 Protein Vector (Rat) (pPM-C-His)

PV272813 500 ng
EUR 723.6

HIRIP3 Protein Vector (Human) (pPM-C-HA)

PV019583 500 ng
EUR 394.8

HIRIP3 Protein Vector (Mouse) (pPM-C-HA)

PV188712 500 ng
EUR 723.6

AAP58286-100UG - HIRIP3 Peptide - middle region

AAP58286-100UG 100ug
EUR 99

HIRIP3 Protein Vector (Human) (pPB-C-His)

PV019581 500 ng
EUR 394.8

HIRIP3 Protein Vector (Human) (pPB-N-His)

PV019582 500 ng
EUR 394.8

HIRIP3 Protein Vector (Human) (pPM-C-His)

PV019584 500 ng
EUR 394.8

HIRIP3 Protein Vector (Mouse) (pPB-C-His)

PV188710 500 ng
EUR 723.6

HIRIP3 Protein Vector (Mouse) (pPB-N-His)

PV188711 500 ng
EUR 723.6

HIRIP3 Protein Vector (Mouse) (pPM-C-His)

PV188713 500 ng
EUR 723.6

Hirip3 3'UTR Luciferase Stable Cell Line

TU109519 1.0 ml Ask for price

HIRIP3 3'UTR Luciferase Stable Cell Line

TU009797 1.0 ml
EUR 1672.8

Hirip3 3'UTR Luciferase Stable Cell Line

TU205784 1.0 ml Ask for price

Hirip3 sgRNA CRISPR Lentivector (Rat) (Target 1)

K7156002 1.0 ug DNA
EUR 184.8

Hirip3 sgRNA CRISPR Lentivector (Rat) (Target 2)

K7156003 1.0 ug DNA
EUR 184.8

Hirip3 sgRNA CRISPR Lentivector (Rat) (Target 3)

K7156004 1.0 ug DNA
EUR 184.8

HIRIP3 sgRNA CRISPR Lentivector (Human) (Target 1)

K0953202 1.0 ug DNA
EUR 184.8

HIRIP3 sgRNA CRISPR Lentivector (Human) (Target 2)

K0953203 1.0 ug DNA
EUR 184.8

HIRIP3 sgRNA CRISPR Lentivector (Human) (Target 3)

K0953204 1.0 ug DNA
EUR 184.8

Hirip3 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K4629702 1.0 ug DNA
EUR 184.8

Hirip3 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K4629703 1.0 ug DNA
EUR 184.8

Hirip3 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K4629704 1.0 ug DNA
EUR 184.8

Human HIRA- interacting protein 3, HIRIP3 ELISA KIT

ELI-38603h 96 Tests
EUR 988.8

Mouse HIRA- interacting protein 3, Hirip3 ELISA KIT

ELI-14456m 96 Tests
EUR 1038

Human HIRA-Interacting Protein 3 (HIRIP3) ELISA Kit

abx387793-96tests 96 tests
EUR 1093.2

Mouse HIRA-interacting protein 3 (HIRIP3) ELISA Kit

abx527166-96tests 96 tests
EUR 687.5

HIRIP3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV)

LV627643 1.0 ug DNA
EUR 818.4

HIRIP3 Lentiviral Vector (Rat) (UbC) (pLenti-GIII-UbC)

LV627647 1.0 ug DNA
EUR 818.4

HIRIP3 Lentiviral Vector (Rat) (EF1a) (pLenti-GIII-EF1a)

LV627648 1.0 ug DNA
EUR 818.4

Hirip3 (Rat) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR500410 2 nmol Ask for price

Hirip3 (Mouse) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR418030 2 nmol Ask for price

HIRIP3 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR305556 2 nmol Ask for price

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

K7156005 3 x 1.0 ug
EUR 451.2

HIRIP3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K0953205 3 x 1.0 ug
EUR 451.2

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)

K4629705 3 x 1.0 ug
EUR 451.2

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)

K7156006 1.0 ug DNA
EUR 200.4

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 2)

K7156007 1.0 ug DNA
EUR 200.4

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)

K7156008 1.0 ug DNA
EUR 200.4

HIRIP3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K0953206 1.0 ug DNA
EUR 200.4

HIRIP3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K0953207 1.0 ug DNA
EUR 200.4

HIRIP3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K0953208 1.0 ug DNA
EUR 200.4

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 1)

K4629706 1.0 ug DNA
EUR 200.4

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 2)

K4629707 1.0 ug DNA
EUR 200.4

Hirip3 sgRNA CRISPR/Cas9 All-in-One Lentivector (Mouse) (Target 3)

K4629708 1.0 ug DNA
EUR 200.4

Hirip3 - Rat, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL703037 5 µg/vial Ask for price

HIRIP3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-C-term-HA)

LV627644 1.0 ug DNA
EUR 818.4

Lenti ORF clone of Human HIRA interacting protein 3 (HIRIP3), mGFP tagged

RC200510L4 10 µg Ask for price

Hirip3 - Mouse, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL507050 5 µg/vial Ask for price

HIRIP3 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL312453 5 µg/vial Ask for price

HIRIP3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-GFP-2A-Puro)

LV627645 1.0 ug DNA
EUR 888

HIRIP3 Lentiviral Vector (Rat) (CMV) (pLenti-GIII-CMV-RFP-2A-Puro)

LV627646 1.0 ug DNA
EUR 888

Hirip3 - Rat, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR703037 5 µg/vial Ask for price

Hirip3 - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR507050 5 µg/vial Ask for price

HIRIP3 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR312453 5 µg/vial Ask for price

3`UTR clone of HIRA interacting protein 3 (HIRIP3) for miRNA target validation

SC202579 10 µg Ask for price

Lenti ORF clone of Human HIRA interacting protein 3 (HIRIP3), Myc-DDK-tagged

RC200510L3 10 µg Ask for price

Hirip3 - Rat shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL703037V 500 ul each Ask for price

Hirip3 - Mouse shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL507050V 500 ul each Ask for price

HIRIP3 - Human shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL312453V 500 ul each Ask for price

Anti-HIRIP3 Antibody

39461 100ul
EUR 479

Anti-HIRIP3 antibody

PAab03871 100 ug
EUR 494.4

Anti-HIRIP3 antibody

STJ29094 100 µl
EUR 332.4
Description: The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Anti-HIRIP3 Antibody

Y058569 100 µl
EUR 145

Rabbit anti-HIRIP3 Antibody

DL98118A-100ul 100 ul
EUR 334
Description: HIRA-interacting protein 3

Rabbit anti-HIRIP3 Antibody

DL98118A-50ul 50 ul
EUR 233.8
Description: HIRA-interacting protein 3

Rabbit anti-HIRIP3 Antibody

YLD3819-100ul 100 ul
EUR 320
Description: Rabbit polyclonal antibody to HIRIP3
In yeast, Asf1 is required for the contribution of the Hir proteins to gene silencing . Right here, we exhibit that Hir1, Hir2, Hir3, and Hpc2 comprise the HIR advanced, which copurifies with the histone deposition protein Asf1. Collectively, the HIR advanced and Asf1 deposit histones onto DNA in a replication-independent method. Histone deposition by the HIR advanced and Asf1 is impaired by a mutation in Asf1 that inhibits HIR binding. These knowledge point out that the HIR advanced and Asf1 proteins operate collectively as a conserved eukaryotic pathway for histone alternative all through the cell cycle.

Leave a Reply

Your email address will not be published.