Inadequate tissue oxygen, or hypoxia, is a central concept in the pathophysiology of ischemic disorders and cancer. Hypoxia promotes extracellular matrix (ECM) remodeling, cellular metabolic adaptation, and cancer cell metastasis. To discover new pathways through which cells respond to hypoxia, we performed a large-scale forward genetic screen in Caenorhabditis elegans and identified a previously uncharacterized receptor tyrosine kinase named HIR-1.
Loss of function in hir-1 phenocopied the impaired ECM integrity associated with hypoxia or deficiency in the oxygen-dependent dual oxidase, heme peroxidases, or cuticular collagens involved in ECM homeostasis. Genetic suppressor screens identified NHR-49 and MDT-15 as transcriptional regulators downstream of HIR-1.
Furthermore, hir-1 mutants showed defects in adapting to and recovering from prolonged severe hypoxia. We propose that C. elegans HIR-1 coordinates hypoxia-inducible factor-independent responses to hypoxia and hypoxia-associated ECM remodeling through mechanisms that are likely conserved in other organisms.
The Candida albicans HIR histone chaperone regulates the yeast-to-hyphae transition by controlling the sensitivity to morphogenesis signals.
Morphological plasticity such as the yeast-to-hyphae transition is a key virulence factor of the human fungal pathogen Candida albicans. Hyphal formation is controlled by a multilayer regulatory network composed of environmental sensing, signaling, transcriptional modulators as well as chromatin modifications. Here, we demonstrate a novel role for the replication-independent HIR histone chaperone complex in fungal morphogenesis. HIR operates as a crucial modulator of hyphal development, since genetic ablation of the HIR complex subunit Hir1 decreases sensitivity to morphogenetic stimuli.
Strikingly, HIR1-deficient cells display altered transcriptional amplitudes upon hyphal initiation, suggesting that Hir1 affects transcription by establishing transcriptional thresholds required for driving morphogenetic cell-fate decisions. Furthermore, ectopic expression of the transcription factor Ume6, which facilitates hyphal maintenance, rescues filamentation defects of hir1Δ/Δ cells, suggesting that Hir1 impacts the early phase of hyphal initiation. Hence, chromatin chaperone-mediated fine-tuning of transcription is crucial for driving morphogenetic conversions in the fungal pathogen C. albicans.
The CAF-1 and Hir Histone Chaperones Associate with Sites of Meiotic Double-Strand Breaks in Budding Yeast.
In the meiotic prophase, programmed DNA double-strand breaks (DSB) are introduced along chromosomes to promote homolog pairing and recombination. Although meiotic DSBs usually occur in nucleosome-depleted, accessible regions of chromatin, their repair by homologous recombination takes place in a nucleosomal environment. Nucleosomes may represent an obstacle for the recombination machinery and their timely eviction and reincorporation into chromatin may influence the outcome of recombination, for instance by stabilizing recombination intermediates.
Here we show in budding yeast that nucleosomes flanking a meiotic DSB are transiently lost during recombination, and that specific histone H3 chaperones, CAF-1 and Hir, are mobilized at meiotic DSBs. However, the absence of these chaperones has no effect on meiotic recombination, suggesting that timely histone reincorporation following their eviction has no influence on the recombination outcome, or that redundant pathways are activated. This study is the first example of the involvement of histone H3 chaperones at naturally occurring, developmentally programmed DNA double-strand breaks.
The histone chaperone complex HIR maintains nucleosome occupancy and counterbalances impaired histone deposition in CAF-1 complex mutants.
Chromatin organization is essential for coordinated gene expression, genome stability, and inheritance of epigenetic information. The main components involved in chromatin assembly are specific complexes such as Chromatin Assembly Factor 1 (CAF-1) and Histone Regulator (HIR), which deposit histones in a DNA synthesis-dependent or -independent manner, respectively. Here, we characterize the role of the plant orthologs Histone Regulator A (HIRA), Ubinuclein (UBN) and Calcineurin Binding protein 1 (CABIN1), which constitute the HIR complex.
Arabidopsis loss-of-function mutants for the various subunits of the complex are viable, but hira mutants show reduced fertility. We show that loss of HIRA reduces extractable histone H3 protein levels and decreases nucleosome occupancy at both actively transcribed genes and heterochromatic regions. Concomitantly, HIRA contributes to maintenance of silencing of pericentromeric repeats and certain transposons.
A genetic analysis based on crosses between mutants deficient in subunits of the CAF-1 and HIR complexes showed that simultaneous loss of both the CAF-1 and HIR histone H3 chaperone complexes severely affects plant survival, growth and reproductive development. Our results suggest that HIRA partially rescues impaired histone deposition in fas mutants to preserve nucleosome occupancy, implying plasticity in histone variant interaction and deposition.
Tissue-specific expression of a soybean hypersensitive-induced response (HIR) protein gene promoter.
A Glycine max gene encoding a putative protein similar to hypersensitive-induced response proteins (HIR) was identified as a gene with preferred expressions in flowers and developing seeds by whole transcriptome gene expression profiling. Its promoter gm-hir1 was cloned and revealed to strongly express a fluorescence reporter gene primarily in integuments, anther tapetum, and seed coat with unique tissue-specificity. Expression in the inner integument was apparent prior to pollination, while expression in the outer integument started to develop from the micropylar end outward as the embryo matured.
IRS1 Antibody (phospho Ser312) |
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| GWB-C94168 | GenWay Biotech | 0.05 ml | Ask for price |
IRS-1 (phospho Ser616) Polyclonal Antibody |
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| ABP54928-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of IRS-1 phospho Ser616) from Human, Mouse, Rat. This IRS-1 phospho Ser616) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S616 |
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IRS-1 (phospho Ser616) Polyclonal Antibody |
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| ABP54928-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of IRS-1 phospho Ser616) from Human, Mouse, Rat. This IRS-1 phospho Ser616) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S616 |
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IRS-1 (phospho Ser616) Polyclonal Antibody |
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| ABP54928-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of IRS-1 phospho Ser616) from Human, Mouse, Rat. This IRS-1 phospho Ser616) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S616 |
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IRS-1 (phospho Ser616) Polyclonal Antibody |
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| E20-60640 | EnoGene | 100ug | EUR 225 |
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Description: Available in various conjugation types. |
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IRS-1 (phospho Ser616) Polyclonal Antibody |
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| E013782 | EnoGene | 100μg/100μl | EUR 255 |
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Description: Available in various conjugation types. |
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IRS-1(Phospho Ser616) Polyclonal Antibody |
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| BT-AP10511-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
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Description: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. |
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IRS-1(Phospho Ser616) Polyclonal Antibody |
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| BT-AP10511-20ul | Jiaxing Korain Biotech Ltd (BT Labs) | 20ul | Ask for price |
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Description: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. |
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IRS-1(Phospho Ser616) Polyclonal Antibody |
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| BT-AP10511-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
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Description: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. |
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IRS-1 (phospho Ser616) Polyclonal Antibody |
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| E44H01124 | EnoGene | 100ul | EUR 255 |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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IRS-1 (phospho Ser616) Polyclonal Antibody |
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| MBS8520414-01mg | MyBiosource | 0.1mg | EUR 305 |
IRS-1 (phospho Ser616) Polyclonal Antibody |
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| MBS8520414-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
IRS-1 (phospho Ser616) Polyclonal Antibody |
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| MBS8520414-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
IRS-1 (phospho Ser616) Polyclonal Antibody |
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| MBS8520414-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
IRS-1 (phospho Ser616) Polyclonal Antibody |
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| MBS8520414-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
IRS-1 (phospho Ser616) Polyclonal Antibody |
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| UB-GEN-3485 | UpingBio | 100 ul | EUR 200 |
OASG03974-100UL - IRS1 Antibody (Phospho-Ser616) |
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| OASG03974-100UL | Aviva Systems Biology | 100ul | EUR 239 |
IRS (phospho Ser616) Polyclonal Antibody |
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| 13782 | SAB | 100ul | EUR 319 |
IRS (Phospho Ser616) Polyclonal Antibody |
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| MBS9458952-005mL | MyBiosource | 0.05mL | EUR 245 |
IRS (Phospho Ser616) Polyclonal Antibody |
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| MBS9458952-01mL | MyBiosource | 0.1mL | EUR 305 |
IRS (Phospho Ser616) Polyclonal Antibody |
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| MBS9458952-5x01mL | MyBiosource | 5x0.1mL | EUR 1230 |
IRS-1 (phospho Ser616) Rabbit Polyclonal Antibody |
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| ES5927-100ul | ELK Biotech | 100ul | EUR 124 |
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Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser616) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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IRS-1 (phospho Ser616) Rabbit Polyclonal Antibody |
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| ES5927-50ul | ELK Biotech | 50ul | EUR 74 |
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Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser616) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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Phospho-IRS1 (Ser616) Blocking Peptide |
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| MBS9616505-1mg | MyBiosource | 1mg | EUR 380 |
Phospho-IRS1 (Ser616) Blocking Peptide |
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| MBS9616505-5x1mg | MyBiosource | 5x1mg | EUR 1650 |
IRS-1, phosphorylated (Ser616) (Insulin Receptor Substrate 1, IRS1) |
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| MBS609061-01mg | MyBiosource | 0.1mg | EUR 595 |
IRS-1, phosphorylated (Ser616) (Insulin Receptor Substrate 1, IRS1) |
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| MBS609061-5x01mg | MyBiosource | 5x0.1mg | EUR 2525 |
OABF01191-100UL - IRS1 Antibody (Phospho-Ser636/Ser639) (OABF01191-100UL) |
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| OABF01191-100UL | Aviva Systems Biology | 100ul | EUR 409 |
Insulin Receptor Substrate 1 Phospho-Ser616 (IRS1 pS616) Antibody |
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| 20-abx329007 | Abbexa |
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Insulin Receptor Substrate 1 Phospho-Ser616 (IRS1 pS616) Antibody |
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| abx329007-100l | Abbexa | 100 µl | EUR 187.5 |
DRP1 (Phospho- Ser616) Antibody |
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| ABF8470 | Nova Lifetech | 100ug | EUR 325 |
Phospho- DRP1 (Ser616) Antibody |
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| ABD2972 | Nova Lifetech | 100ug | EUR 325 |
Phospho- DRP1 (Ser616) Antibody |
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| ABD2981 | Nova Lifetech | 100ug | EUR 325 |
Phospho-DRP1 (Ser616) Antibody |
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| E19-2972-1 | EnoGene | 50ug/50ul | EUR 145 |
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Description: Available in various conjugation types. |
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Phospho-DRP1 (Ser616) Antibody |
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| E19-2972-2 | EnoGene | 100ug/100ul | EUR 225 |
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Description: Available in various conjugation types. |
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Phospho-DRP1 (Ser616) Antibody |
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| DF2972 | Affbiotech | 200ul | EUR 420 |
Phospho-DRP1 (Ser616) Antibody |
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| AF8470 | Affbiotech | 200ul | EUR 540 |
Phospho-DRP1 (Ser616) Antibody |
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| AF8470-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-DRP1 (Ser616) Antibody |
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| AF8470-200ul | Affinity Biosciences | 200ul | EUR 450 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS8513652-005mg | MyBiosource | 0.05mg | EUR 235 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS8513652-01mg | MyBiosource | 0.1mg | EUR 305 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS8513652-01mLAF405M | MyBiosource | 0.1mL(AF405M) | EUR 465 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS8513652-01mLAF546 | MyBiosource | 0.1mL(AF546) | EUR 465 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS8513652-01mLAF750 | MyBiosource | 0.1mL(AF750) | EUR 465 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS9614463-005mL | MyBiosource | 0.05mL | EUR 245 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS9614463-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS9614463-02mL | MyBiosource | 0.2mL | EUR 370 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS9614463-5x02mL | MyBiosource | 5x0.2mL | EUR 1605 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS9604437-01mL | MyBiosource | 0.1mL | EUR 260 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS9604437-02mL | MyBiosource | 0.2mL | EUR 305 |
Phospho-DRP1 (Ser616) Antibody |
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| MBS9604437-5x02mL | MyBiosource | 5x0.2mL | EUR 1220 |
Phospho-DRP1 (Ser616) Antibody |
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| DF2972-100ul | Affinity Biosciences | 100ul | EUR 168 |
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Description: WB,ELISA(peptide) |
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Phospho-DRP1 (Ser616) Antibody |
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| DF2972-200ul | Affinity Biosciences | 200ul | EUR 210 |
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Description: WB,ELISA(peptide) |
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Kv4.2/KCND2 (Phospho- Ser616) Antibody |
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| ABF8074 | Nova Lifetech | 100ug | EUR 325 |
Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ABP54999-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of Kv4.2 phospho Ser616) from Human, Mouse, Rat. This Kv4.2 phospho Ser616) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Kv4.2 around the phosphorylation site of S616 |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ABP54999-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of Kv4.2 phospho Ser616) from Human, Mouse, Rat. This Kv4.2 phospho Ser616) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Kv4.2 around the phosphorylation site of S616 |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ABP54999-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of Kv4.2 phospho Ser616) from Human, Mouse, Rat. This Kv4.2 phospho Ser616) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Kv4.2 around the phosphorylation site of S616 |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| E013756 | EnoGene | 100μg/100μl | EUR 255 |
|
Description: Available in various conjugation types. |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| E20-61005 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
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Kv4.2(Phospho Ser616) Polyclonal Antibody |
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| BT-AP10804-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
|
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as i |
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Kv4.2(Phospho Ser616) Polyclonal Antibody |
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| BT-AP10804-20ul | Jiaxing Korain Biotech Ltd (BT Labs) | 20ul | Ask for price |
|
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as i |
|||
Kv4.2(Phospho Ser616) Polyclonal Antibody |
|||
| BT-AP10804-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
|
Description: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member mediates a rapidly inactivating, A-type outward potassium current which is not under the control of the N terminus as i |
|||
Kv4.2 (phospho Ser616) Polyclonal Antibody |
|||
| E44H00229 | EnoGene | 100ul | EUR 255 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| MBS8520779-01mg | MyBiosource | 0.1mg | EUR 305 |
Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| MBS8520779-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| MBS8520779-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| MBS8520779-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| MBS8520779-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
Kv4.2 (Phospho Ser616) Polyclonal Antibody |
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| MBS9458926-005mL | MyBiosource | 0.05mL | EUR 245 |
Kv4.2 (Phospho Ser616) Polyclonal Antibody |
|||
| MBS9458926-01mL | MyBiosource | 0.1mL | EUR 305 |
Kv4.2 (Phospho Ser616) Polyclonal Antibody |
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| MBS9458926-5x01mL | MyBiosource | 5x0.1mL | EUR 1230 |
Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| UB-GEN-15770 | UpingBio | 100 ul | EUR 200 |
Phospho-IRS-1 (Ser616) Antibody |
|||
| E11-184423 | EnoGene | 100ug/100ul | EUR 225 |
|
Description: Available in various conjugation types. |
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Phospho-IRS-1 (Ser616) Antibody |
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| MBS8529055-01mg | MyBiosource | 0.1mg | EUR 305 |
Phospho-IRS-1 (Ser616) Antibody |
|||
| MBS8529055-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
Phospho-IRS-1 (Ser616) Antibody |
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| MBS8529055-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
Phospho-IRS-1 (Ser616) Antibody |
|||
| MBS8529055-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
Phospho-IRS-1 (Ser616) Antibody |
|||
| MBS8529055-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
IRS-1 (Phospho-Ser616) Antibody |
|||
| A0447-100ul | Assay Biotech | 100μl | EUR 217 |
|
Description: IRS-1 (Phospho-Ser616) Rabbit Polyclonal Antibody |
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IRS-1 (Phospho-Ser616) Antibody |
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| A0447-50ul | Assay Biotech | 50μl | EUR 143.5 |
|
Description: IRS-1 (Phospho-Ser616) Rabbit Polyclonal Antibody |
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Phospho-Kv4.2/KCND2 (Ser616) Antibody |
|||
| AF8074 | Affbiotech | 200ul | EUR 540 |
Phospho-Kv4.2/KCND2 (Ser616) Antibody |
|||
| AF8074-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-Kv4.2/KCND2 (Ser616) Antibody |
|||
| AF8074-200ul | Affinity Biosciences | 200ul | EUR 450 |
Phospho-Kv4.2/KCND2 (Ser616) Antibody |
|||
| MBS9614075-005mL | MyBiosource | 0.05mL | EUR 245 |
Phospho-Kv4.2/KCND2 (Ser616) Antibody |
|||
| MBS9614075-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-Kv4.2/KCND2 (Ser616) Antibody |
|||
| MBS9614075-02mL | MyBiosource | 0.2mL | EUR 370 |
Phospho-Kv4.2/KCND2 (Ser616) Antibody |
|||
| MBS9614075-5x02mL | MyBiosource | 5x0.2mL | EUR 1605 |
Kv4.2 (phospho Ser616) Rabbit Polyclonal Antibody |
|||
| ES5998-100ul | ELK Biotech | 100ul | EUR 124 |
|
Description: A Rabbit Polyclonal antibody against Kv4.2 (phospho Ser616) from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA |
|||
Kv4.2 (phospho Ser616) Rabbit Polyclonal Antibody |
|||
| ES5998-50ul | ELK Biotech | 50ul | EUR 74 |
|
Description: A Rabbit Polyclonal antibody against Kv4.2 (phospho Ser616) from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA |
|||
IRS1 Antibody (phospho Tyr941) |
|||
| GWB-70BA06 | GenWay Biotech | 0.05 ml | Ask for price |
IRS1 Antibody (phospho Tyr896) |
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| GWB-F7F2BE | GenWay Biotech | 0.05 ml | Ask for price |
IRS1 Antibody (phospho Tyr1179) |
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| GWB-570DB1 | GenWay Biotech | 0.05 ml | Ask for price |
Phospho-IRS1 (Ser1101) Antibody |
|||
| AF4421 | Affbiotech | 200ul | EUR 540 |
Phospho-IRS1 (Ser1101) Antibody |
|||
| AF4421-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-IRS1 (Ser1101) Antibody |
|||
| AF4421-200ul | Affinity Biosciences | 200ul | EUR 450 |
Phospho-IRS1 (Ser1101) Antibody |
|||
| MBS9613222-005mL | MyBiosource | 0.05mL | EUR 245 |
Phospho-IRS1 (Ser1101) Antibody |
|||
| MBS9613222-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-IRS1 (Ser1101) Antibody |
|||
| MBS9613222-02mL | MyBiosource | 0.2mL | EUR 370 |
Phospho-IRS1 (Ser1101) Antibody |
|||
| MBS9613222-5x02mL | MyBiosource | 5x0.2mL | EUR 1605 |
Phospho-IRS1 (Ser307) Antibody |
|||
| AF3272 | Affbiotech | 200ul | EUR 420 |
Phospho-IRS1 (Ser307) Antibody |
|||
| AF3272-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser307) Antibody |
|||
| AF3272-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser312) Antibody |
|||
| AF3273 | Affbiotech | 200ul | EUR 420 |
Phospho-IRS1 (Ser312) Antibody |
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| AF3273-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser312) Antibody |
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| AF3273-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser636) Antibody |
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| AF3274 | Affbiotech | 200ul | EUR 420 |
Phospho-IRS1 (Ser636) Antibody |
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| AF3274-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser636) Antibody |
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| AF3274-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser639) Antibody |
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| AF3275 | Affbiotech | 200ul | EUR 420 |
Phospho-IRS1 (Ser639) Antibody |
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| AF3275-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser639) Antibody |
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| AF3275-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser639) Antibody |
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| CSB-PA004394- | Cusabio | each | EUR 402 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser639). Recognizes Phospho-IRS1 (Ser639) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser639) Antibody |
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| CSB-PA004394-100ul | Cusabio | 100ul | EUR 434.4 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser639). Recognizes Phospho-IRS1 (Ser639) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser636) Antibody |
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| CSB-PA577877- | Cusabio | each | EUR 402 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser636). Recognizes Phospho-IRS1 (Ser636) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser636) Antibody |
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| CSB-PA577877-100ul | Cusabio | 100ul | EUR 434.4 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser636). Recognizes Phospho-IRS1 (Ser636) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser307) Antibody |
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| CSB-PA224848- | Cusabio | each | EUR 402 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser307). Recognizes Phospho-IRS1 (Ser307) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100 |
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Phospho-IRS1 (Ser307) Antibody |
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| CSB-PA224848-100ul | Cusabio | 100ul | EUR 434.4 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser307). Recognizes Phospho-IRS1 (Ser307) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100 |
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Phospho-IRS1 (Ser312) Antibody |
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| CSB-PA174165- | Cusabio | each | EUR 402 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser312). Recognizes Phospho-IRS1 (Ser312) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
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Phospho-IRS1 (Ser312) Antibody |
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| CSB-PA174165-100ul | Cusabio | 100ul | EUR 434.4 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser312). Recognizes Phospho-IRS1 (Ser312) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
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Phospho-IRS1 (Ser312) Antibody |
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| MBS7132913-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-IRS1 (Ser312) Antibody |
|||
| MBS7132913-5x01mL | MyBiosource | 5x0.1mL | EUR 1395 |
Phospho-IRS1 (Ser307) Antibody |
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| MBS7132938-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-IRS1 (Ser307) Antibody |
|||
| MBS7132938-5x01mL | MyBiosource | 5x0.1mL | EUR 1395 |
Phospho-IRS1 (Ser636) Antibody |
|||
| MBS7133325-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-IRS1 (Ser636) Antibody |
|||
| MBS7133325-5x01mL | MyBiosource | 5x0.1mL | EUR 1395 |
Phospho-IRS1 (Ser639) Antibody |
|||
| MBS7133326-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-IRS1 (Ser639) Antibody |
|||
| MBS7133326-5x01mL | MyBiosource | 5x0.1mL | EUR 1395 |
IRS2 (Phospho- Ser1100) Antibody |
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| ABF8383 | Nova Lifetech | 100ug | EUR 325 |
Phospho-IRS (Ser616) Antibody (Clone HIR-B1) |
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| 3105-100 | Biovision | each | EUR 430.8 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| AF4422 | Affbiotech | 200ul | EUR 540 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| AF4422-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| AF4422-200ul | Affinity Biosciences | 200ul | EUR 450 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| MBS9613223-005mL | MyBiosource | 0.05mL | EUR 245 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| MBS9613223-01mL | MyBiosource | 0.1mL | EUR 310 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| MBS9613223-02mL | MyBiosource | 0.2mL | EUR 370 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| MBS9613223-5x02mL | MyBiosource | 5x0.2mL | EUR 1605 |
Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| E-AB-20908-120uL | Elabscience Biotech | 120uL | EUR 240 |
|
Description: Unconjugated |
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Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| E-AB-20908-200uL | Elabscience Biotech | 200uL | EUR 399 |
|
Description: Unconjugated |
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Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| E-AB-20908-20uL | Elabscience Biotech | 20uL | EUR 73 |
|
Description: Unconjugated |
|||
Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| E-AB-20908-60uL | Elabscience Biotech | 60uL | EUR 143 |
|
Description: Unconjugated |
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Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| RD85874A-120uL | Reddot Biotech | 120μL | EUR 360 |
|
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. |
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Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| RD85874A-200uL | Reddot Biotech | 200μL | EUR 630 |
|
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. |
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Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| RD85874A-20uL | Reddot Biotech | 20μL | EUR 109.5 |
|
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. |
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Phospho-IRS1 (Ser636) Polyclonal Antibody |
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| RD85874A-60uL | Reddot Biotech | 60μL | EUR 214.5 |
|
Description: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit. |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| ABP50340-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser1101) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser1101) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S1101 |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| ABP50340-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser1101) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser1101) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S1101 |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| ABP50340-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser1101) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser1101) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S1101 |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| E20-60145 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| E013783 | EnoGene | 100μg/100μl | EUR 255 |
|
Description: Available in various conjugation types. |
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IRS-1(Phospho Ser1101) Polyclonal Antibody |
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| BT-AP10507-100ul | Jiaxing Korain Biotech Ltd (BT Labs) | 100ul | Ask for price |
|
Description: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. |
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IRS-1(Phospho Ser1101) Polyclonal Antibody |
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| BT-AP10507-20ul | Jiaxing Korain Biotech Ltd (BT Labs) | 20ul | Ask for price |
|
Description: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. |
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IRS-1(Phospho Ser1101) Polyclonal Antibody |
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| BT-AP10507-50ul | Jiaxing Korain Biotech Ltd (BT Labs) | 50ul | Ask for price |
|
Description: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| E44H00813 | EnoGene | 100ul | EUR 255 |
|
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| MBS9242007-01mL | MyBiosource | 0.1mL | EUR 425 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| MBS9242007-5x01mL | MyBiosource | 5x0.1mL | EUR 1887 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| MBS8519919-01mg | MyBiosource | 0.1mg | EUR 305 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| MBS8519919-01mLAF405L | MyBiosource | 0.1mL(AF405L) | EUR 465 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| MBS8519919-01mLAF405S | MyBiosource | 0.1mL(AF405S) | EUR 465 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| MBS8519919-01mLAF610 | MyBiosource | 0.1mL(AF610) | EUR 465 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| MBS8519919-01mLAF635 | MyBiosource | 0.1mL(AF635) | EUR 465 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| UB-GEN-3444 | UpingBio | 100 ul | EUR 200 |
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50341-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50341-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50341-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50342-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50342-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50342-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ABP50343-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser636) from Human, Mouse, Rat. This IRS-1 phospho Ser636) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S636 |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ABP50343-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser636) from Human, Mouse, Rat. This IRS-1 phospho Ser636) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S636 |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ABP50343-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser636) from Human, Mouse, Rat. This IRS-1 phospho Ser636) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S636 |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ABP50344-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser639) from Human, Mouse, Rat. This IRS-1 phospho Ser639) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S639 |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ABP50344-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser639) from Human, Mouse, Rat. This IRS-1 phospho Ser639) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S639 |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ABP50344-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser639) from Human, Mouse, Rat. This IRS-1 phospho Ser639) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S639 |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ABP50345-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser794) from Human, Mouse, Rat. This IRS-1 phospho Ser794) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S794 |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ABP50345-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser794) from Human, Mouse, Rat. This IRS-1 phospho Ser794) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S794 |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ABP50345-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser794) from Human, Mouse, Rat. This IRS-1 phospho Ser794) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S794 |
|||
A 5′-deletion study showed that the promoter can be truncated to 600 bp long relative to the translation start site without affecting expression. A positive regulatory element was identified between 600 and 481 bp that controls expression in the inner integument, with no noticeable effect on expression in the outer integument or tapetum. Additionally, removal of the 5’UTR intron had no effect on levels or location of gm-hir1 expression while truncation to 370 bp resulted in a complete loss of expression suggesting that elements controlling both the outer integument and tapetum expression are located within the 481-370 bp region.