Inadequate tissue oxygen, or hypoxia, is a central concept in the pathophysiology of ischemic disorders and cancer. Hypoxia promotes extracellular matrix (ECM) remodeling, cellular metabolic adaptation, and cancer cell metastasis. To discover new pathways through which cells respond to hypoxia, we performed a large-scale forward genetic screen in Caenorhabditis elegans and identified a previously uncharacterized receptor tyrosine kinase named HIR-1.
Loss of function in hir-1 phenocopied the impaired ECM integrity associated with hypoxia or deficiency in the oxygen-dependent dual oxidase, heme peroxidases, or cuticular collagens involved in ECM homeostasis. Genetic suppressor screens identified NHR-49 and MDT-15 as transcriptional regulators downstream of HIR-1.
Furthermore, hir-1 mutants showed defects in adapting to and recovering from prolonged severe hypoxia. We propose that C. elegans HIR-1 coordinates hypoxia-inducible factor-independent responses to hypoxia and hypoxia-associated ECM remodeling through mechanisms that are likely conserved in other organisms.
The Candida albicans HIR histone chaperone regulates the yeast-to-hyphae transition by controlling the sensitivity to morphogenesis signals.
Morphological plasticity such as the yeast-to-hyphae transition is a key virulence factor of the human fungal pathogen Candida albicans. Hyphal formation is controlled by a multilayer regulatory network composed of environmental sensing, signaling, transcriptional modulators as well as chromatin modifications. Here, we demonstrate a novel role for the replication-independent HIR histone chaperone complex in fungal morphogenesis. HIR operates as a crucial modulator of hyphal development, since genetic ablation of the HIR complex subunit Hir1 decreases sensitivity to morphogenetic stimuli.
Strikingly, HIR1-deficient cells display altered transcriptional amplitudes upon hyphal initiation, suggesting that Hir1 affects transcription by establishing transcriptional thresholds required for driving morphogenetic cell-fate decisions. Furthermore, ectopic expression of the transcription factor Ume6, which facilitates hyphal maintenance, rescues filamentation defects of hir1Δ/Δ cells, suggesting that Hir1 impacts the early phase of hyphal initiation. Hence, chromatin chaperone-mediated fine-tuning of transcription is crucial for driving morphogenetic conversions in the fungal pathogen C. albicans.
The CAF-1 and Hir Histone Chaperones Associate with Sites of Meiotic Double-Strand Breaks in Budding Yeast.
In the meiotic prophase, programmed DNA double-strand breaks (DSB) are introduced along chromosomes to promote homolog pairing and recombination. Although meiotic DSBs usually occur in nucleosome-depleted, accessible regions of chromatin, their repair by homologous recombination takes place in a nucleosomal environment. Nucleosomes may represent an obstacle for the recombination machinery and their timely eviction and reincorporation into chromatin may influence the outcome of recombination, for instance by stabilizing recombination intermediates.
Here we show in budding yeast that nucleosomes flanking a meiotic DSB are transiently lost during recombination, and that specific histone H3 chaperones, CAF-1 and Hir, are mobilized at meiotic DSBs. However, the absence of these chaperones has no effect on meiotic recombination, suggesting that timely histone reincorporation following their eviction has no influence on the recombination outcome, or that redundant pathways are activated. This study is the first example of the involvement of histone H3 chaperones at naturally occurring, developmentally programmed DNA double-strand breaks.
The histone chaperone complex HIR maintains nucleosome occupancy and counterbalances impaired histone deposition in CAF-1 complex mutants.
Chromatin organization is essential for coordinated gene expression, genome stability, and inheritance of epigenetic information. The main components involved in chromatin assembly are specific complexes such as Chromatin Assembly Factor 1 (CAF-1) and Histone Regulator (HIR), which deposit histones in a DNA synthesis-dependent or -independent manner, respectively. Here, we characterize the role of the plant orthologs Histone Regulator A (HIRA), Ubinuclein (UBN) and Calcineurin Binding protein 1 (CABIN1), which constitute the HIR complex.
Arabidopsis loss-of-function mutants for the various subunits of the complex are viable, but hira mutants show reduced fertility. We show that loss of HIRA reduces extractable histone H3 protein levels and decreases nucleosome occupancy at both actively transcribed genes and heterochromatic regions. Concomitantly, HIRA contributes to maintenance of silencing of pericentromeric repeats and certain transposons.
A genetic analysis based on crosses between mutants deficient in subunits of the CAF-1 and HIR complexes showed that simultaneous loss of both the CAF-1 and HIR histone H3 chaperone complexes severely affects plant survival, growth and reproductive development. Our results suggest that HIRA partially rescues impaired histone deposition in fas mutants to preserve nucleosome occupancy, implying plasticity in histone variant interaction and deposition.
Tissue-specific expression of a soybean hypersensitive-induced response (HIR) protein gene promoter.
A Glycine max gene encoding a putative protein similar to hypersensitive-induced response proteins (HIR) was identified as a gene with preferred expressions in flowers and developing seeds by whole transcriptome gene expression profiling. Its promoter gm-hir1 was cloned and revealed to strongly express a fluorescence reporter gene primarily in integuments, anther tapetum, and seed coat with unique tissue-specificity. Expression in the inner integument was apparent prior to pollination, while expression in the outer integument started to develop from the micropylar end outward as the embryo matured.
IRS-1 (phospho Ser616) Polyclonal Antibody |
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| E013782 | EnoGene | 100μg/100μl | EUR 255 |
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Description: Available in various conjugation types. |
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IRS-1 (phospho Ser616) Polyclonal Antibody |
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| E20-60640 | EnoGene | 100ug | EUR 225 |
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Description: Available in various conjugation types. |
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DRP1 (Phospho- Ser616) Antibody |
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| ABF8470 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- DRP1 (Ser616) Antibody |
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| ABD2972 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- DRP1 (Ser616) Antibody |
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| ABD2981 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho-DRP1 (Ser616) Antibody |
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| DF2972 | Affbiotech | 200ul | EUR 420 |
Phospho-DRP1 (Ser616) Antibody |
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| AF8470 | Affinity Biosciences | 100ul | EUR 350 |
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Description: Human,Mouse,Rat |
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Phospho-DRP1 (Ser616) Antibody |
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| AF8470-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-DRP1 (Ser616) Antibody |
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| AF8470-200ul | Affinity Biosciences | 200ul | EUR 450 |
Phospho-DRP1 (Ser616) Antibody |
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| E19-2972-1 | EnoGene | 50ug/50ul | EUR 145 |
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Description: Available in various conjugation types. |
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Phospho-DRP1 (Ser616) Antibody |
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| E19-2972-2 | EnoGene | 100ug/100ul | EUR 225 |
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Description: Available in various conjugation types. |
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Kv4.2/KCND2 (Phospho- Ser616) Antibody |
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| ABF8074 | Lifescience Market | 100 ug | EUR 525.6 |
Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ABP54999-003ml | Abbkine | 0.03ml | EUR 189.6 |
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Description: A polyclonal antibody for detection of Kv4.2 phospho Ser616) from Human, Mouse, Rat. This Kv4.2 phospho Ser616) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Kv4.2 around the phosphorylation site of S616 |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ABP54999-01ml | Abbkine | 0.1ml | EUR 346.8 |
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Description: A polyclonal antibody for detection of Kv4.2 phospho Ser616) from Human, Mouse, Rat. This Kv4.2 phospho Ser616) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Kv4.2 around the phosphorylation site of S616 |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ABP54999-02ml | Abbkine | 0.2ml | EUR 496.8 |
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Description: A polyclonal antibody for detection of Kv4.2 phospho Ser616) from Human, Mouse, Rat. This Kv4.2 phospho Ser616) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human Kv4.2 around the phosphorylation site of S616 |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ES5998-100ul | ELK Biotech | 100ul | EUR 334.8 |
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Description: A Rabbit Polyclonal antibody against Kv4.2 (phospho Ser616) from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| ES5998-50ul | ELK Biotech | 50ul | EUR 248.4 |
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Description: A Rabbit Polyclonal antibody against Kv4.2 (phospho Ser616) from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| E013756 | EnoGene | 100μg/100μl | EUR 255 |
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Description: Available in various conjugation types. |
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Kv4.2 (phospho Ser616) Polyclonal Antibody |
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| E20-61005 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
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Phospho-IRS-1 (Ser616) Antibody |
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| E11-184423 | EnoGene | 100ug/100ul | EUR 225 |
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Description: Available in various conjugation types. |
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Phospho-Kv4.2/KCND2 (Ser616) Antibody |
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| AF8074 | Affinity Biosciences | 100ul | EUR 350 |
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Description: Human,Mouse,Rat |
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Phospho-Kv4.2/KCND2 (Ser616) Antibody |
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| AF8074-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-Kv4.2/KCND2 (Ser616) Antibody |
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| AF8074-200ul | Affinity Biosciences | 200ul | EUR 450 |
Insulin Receptor Substrate 1 Phospho-Ser616 (IRS1 pS616) Antibody |
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| 20-abx329007 | Abbexa |
|
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IRS2 (Phospho- Ser1100) Antibody |
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| ABF8383 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho-IRS1 (Ser1101) Antibody |
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| AF4421 | Affinity Biosciences | 100ul | EUR 350 |
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Description: Human,Mouse,Rat |
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Phospho-IRS1 (Ser1101) Antibody |
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| AF4421-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-IRS1 (Ser1101) Antibody |
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| AF4421-200ul | Affinity Biosciences | 200ul | EUR 450 |
Phospho-IRS1 (Ser312) Antibody |
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| CSB-PA174165- | Cusabio | each | EUR 402 |
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Description: A polyclonal antibody against Phospho-IRS1 (Ser312). Recognizes Phospho-IRS1 (Ser312) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
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Phospho-IRS1 (Ser312) Antibody |
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| CSB-PA174165-100ul | Cusabio | 100ul | EUR 434.4 |
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Description: A polyclonal antibody against Phospho-IRS1 (Ser312). Recognizes Phospho-IRS1 (Ser312) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000 |
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Phospho-IRS1 (Ser639) Antibody |
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| CSB-PA004394- | Cusabio | each | EUR 402 |
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Description: A polyclonal antibody against Phospho-IRS1 (Ser639). Recognizes Phospho-IRS1 (Ser639) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser639) Antibody |
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| CSB-PA004394-100ul | Cusabio | 100ul | EUR 434.4 |
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Description: A polyclonal antibody against Phospho-IRS1 (Ser639). Recognizes Phospho-IRS1 (Ser639) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser307) Antibody |
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| CSB-PA224848- | Cusabio | each | EUR 402 |
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Description: A polyclonal antibody against Phospho-IRS1 (Ser307). Recognizes Phospho-IRS1 (Ser307) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100 |
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Phospho-IRS1 (Ser307) Antibody |
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| CSB-PA224848-100ul | Cusabio | 100ul | EUR 434.4 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser307). Recognizes Phospho-IRS1 (Ser307) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100 |
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Phospho-IRS1 (Ser636) Antibody |
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| CSB-PA577877- | Cusabio | each | EUR 402 |
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Description: A polyclonal antibody against Phospho-IRS1 (Ser636). Recognizes Phospho-IRS1 (Ser636) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser636) Antibody |
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| CSB-PA577877-100ul | Cusabio | 100ul | EUR 434.4 |
|
Description: A polyclonal antibody against Phospho-IRS1 (Ser636). Recognizes Phospho-IRS1 (Ser636) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100 |
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Phospho-IRS1 (Ser307) Antibody |
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| AF3272 | Affinity Biosciences | 100ul | EUR 280 |
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Description: Human,Mouse,Rat,Monkey |
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Phospho-IRS1 (Ser312) Antibody |
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| AF3273 | Affinity Biosciences | 100ul | EUR 280 |
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Description: Human,Mouse,Rat,Monkey |
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Phospho-IRS1 (Ser636) Antibody |
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| AF3274 | Affinity Biosciences | 100ul | EUR 280 |
|
Description: Human,Mouse,Rat,Monkey |
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Phospho-IRS1 (Ser639) Antibody |
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| AF3275 | Affinity Biosciences | 100ul | EUR 280 |
|
Description: Human,Mouse,Rat,Monkey |
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Phospho-IRS1 (Ser307) Antibody |
|||
| AF3272-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser307) Antibody |
|||
| AF3272-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser312) Antibody |
|||
| AF3273-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser312) Antibody |
|||
| AF3273-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser636) Antibody |
|||
| AF3274-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser636) Antibody |
|||
| AF3274-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser639) Antibody |
|||
| AF3275-100ul | Affinity Biosciences | 100ul | EUR 280 |
Phospho-IRS1 (Ser639) Antibody |
|||
| AF3275-200ul | Affinity Biosciences | 200ul | EUR 350 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| AF4422 | Affinity Biosciences | 100ul | EUR 350 |
|
Description: Human,Mouse,Rat |
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Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| AF4422-100ul | Affinity Biosciences | 100ul | EUR 350 |
Phospho-IRS1 (Ser318)[Ser323] Antibody |
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| AF4422-200ul | Affinity Biosciences | 200ul | EUR 450 |
Phospho-IRS (Ser616) Antibody (Clone HIR-B1) |
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| 3105-100 | Biovision | each | EUR 430.8 |
IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| ABP50340-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser1101) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser1101) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S1101 |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| ABP50340-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser1101) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser1101) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S1101 |
|||
IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| ABP50340-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser1101) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser1101) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S1101 |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| ES1339-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser1101) from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
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| ES1339-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser1101) from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| E013783 | EnoGene | 100μg/100μl | EUR 255 |
|
Description: Available in various conjugation types. |
|||
IRS-1 (phospho Ser1101) Polyclonal Antibody |
|||
| E20-60145 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50341-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50341-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50341-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50342-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50342-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ABP50342-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser307) from Human, Mouse, Rat. This IRS-1 phospho Ser307) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S307 |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ABP50343-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser636) from Human, Mouse, Rat. This IRS-1 phospho Ser636) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S636 |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ABP50343-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser636) from Human, Mouse, Rat. This IRS-1 phospho Ser636) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S636 |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ABP50343-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser636) from Human, Mouse, Rat. This IRS-1 phospho Ser636) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S636 |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ABP50344-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser639) from Human, Mouse, Rat. This IRS-1 phospho Ser639) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S639 |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ABP50344-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser639) from Human, Mouse, Rat. This IRS-1 phospho Ser639) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S639 |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ABP50344-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser639) from Human, Mouse, Rat. This IRS-1 phospho Ser639) antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S639 |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ABP50345-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser794) from Human, Mouse, Rat. This IRS-1 phospho Ser794) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S794 |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ABP50345-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser794) from Human, Mouse, Rat. This IRS-1 phospho Ser794) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S794 |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ABP50345-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser794) from Human, Mouse, Rat. This IRS-1 phospho Ser794) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S794 |
|||
IRS-1 (phospho Ser312) Polyclonal Antibody |
|||
| ABP50451-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser312) from Human, Mouse, Rat. This IRS-1 phospho Ser312) antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S312 |
|||
IRS-1 (phospho Ser312) Polyclonal Antibody |
|||
| ABP50451-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser312) from Human, Mouse, Rat. This IRS-1 phospho Ser312) antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S312 |
|||
IRS-1 (phospho Ser312) Polyclonal Antibody |
|||
| ABP50451-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser312) from Human, Mouse, Rat. This IRS-1 phospho Ser312) antibody is for WB , IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S312 |
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IRS-1 (phospho Ser323) Polyclonal Antibody |
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| ABP54929-003ml | Abbkine | 0.03ml | EUR 189.6 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser323) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser323) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S323 |
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IRS-1 (phospho Ser323) Polyclonal Antibody |
|||
| ABP54929-01ml | Abbkine | 0.1ml | EUR 346.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser323) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser323) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S323 |
|||
IRS-1 (phospho Ser323) Polyclonal Antibody |
|||
| ABP54929-02ml | Abbkine | 0.2ml | EUR 496.8 |
|
Description: A polyclonal antibody for detection of IRS-1 phospho Ser323) from Human, Mouse, Rat, Monkey. This IRS-1 phospho Ser323) antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human IRS-1 around the phosphorylation site of S323 |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ES1340-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser307) from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
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IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ES1340-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser307) from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ES1341-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser307) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| ES1341-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser307) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ES1342-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser636) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| ES1342-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser636) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ES1343-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser639) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| ES1343-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser639) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ES1344-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser794) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| ES1344-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser794) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser312) Polyclonal Antibody |
|||
| ES1450-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser312) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA |
|||
IRS-1 (phospho Ser312) Polyclonal Antibody |
|||
| ES1450-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser312) from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IF, WB, ELISA |
|||
IRS-1 (phospho Ser323) Polyclonal Antibody |
|||
| ES5928-100ul | ELK Biotech | 100ul | EUR 334.8 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser323) from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser323) Polyclonal Antibody |
|||
| ES5928-50ul | ELK Biotech | 50ul | EUR 248.4 |
|
Description: A Rabbit Polyclonal antibody against IRS-1 (phospho Ser323) from Human/Mouse/Rat/Monkey. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA |
|||
IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| E20-60146 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
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IRS-1 (phospho Ser307) Polyclonal Antibody |
|||
| E20-60147 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
|||
IRS-1 (phospho Ser636) Polyclonal Antibody |
|||
| E20-60148 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
|||
IRS-1 (phospho Ser639) Polyclonal Antibody |
|||
| E20-60149 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
|||
IRS-1 (phospho Ser794) Polyclonal Antibody |
|||
| E20-60150 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
|||
IRS-1 (phospho Ser312) Polyclonal Antibody |
|||
| E20-60571 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
|||
IRS-1 (phospho Ser323) Polyclonal Antibody |
|||
| E20-60881 | EnoGene | 100ug | EUR 225 |
|
Description: Available in various conjugation types. |
|||
Phospho- IRS- 1 (Ser1101) Antibody |
|||
| ABF3622 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser307) Antibody |
|||
| ABF3272 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser312) Antibody |
|||
| ABF3273 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser636) Antibody |
|||
| ABF3274 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser639) Antibody |
|||
| ABF3275 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser302) Antibody |
|||
| ABF3623 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser318) Antibody |
|||
| ABF3624 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser612) Antibody |
|||
| ABF3625 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- IRS- 1 (Ser789) Antibody |
|||
| ABF3626 | Lifescience Market | 100 ug | EUR 525.6 |
IRS1 antibody (Ser1101) |
|||
| 70R-31318 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser1101) |
|||
IRS1 antibody (Ser307) |
|||
| 70R-31072 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser307) |
|||
IRS1 antibody (Ser612) |
|||
| 70R-31320 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser612) |
|||
IRS1 antibody (Ser312) |
|||
| 70R-37221 | Fitzgerald | 100 ug | EUR 418.8 |
|
Description: Rabbit Polyclonal IRS1 antibody (Ser312) |
|||
IRS1 antibody (Ser636) |
|||
| 70R-37296 | Fitzgerald | 100 ug | EUR 418.8 |
|
Description: Rabbit Polyclonal IRS1 antibody (Ser636) |
|||
IRS1 antibody (Ser639) |
|||
| 70R-37297 | Fitzgerald | 100 ug | EUR 418.8 |
|
Description: Rabbit Polyclonal IRS1 antibody (Ser639) |
|||
IRS1 antibody (Ser307) |
|||
| 70R-37301 | Fitzgerald | 100 ug | EUR 418.8 |
|
Description: Rabbit Polyclonal IRS1 antibody (Ser307) |
|||
IRS1 antibody (Ser612) |
|||
| 70R-37439 | Fitzgerald | 100 ug | EUR 418.8 |
|
Description: Rabbit Polyclonal IRS1 antibody (Ser612) |
|||
IRS1 antibody (Ser307) |
|||
| 70R-34208 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser307) |
|||
IRS1 antibody (Ser312) |
|||
| 70R-34210 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser312) |
|||
IRS1 antibody (Ser636) |
|||
| 70R-34212 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser636) |
|||
IRS1 antibody (Ser639) |
|||
| 70R-34214 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser639) |
|||
IRS1 antibody (Ser794) |
|||
| 70R-35835 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser794) |
|||
IRS1 antibody (Ser323) |
|||
| 70R-35928 | Fitzgerald | 100 ug | EUR 392.4 |
|
Description: Rabbit polyclonal IRS1 antibody (Ser323) |
|||
Phospho-DRP1 (Ser616) Blocking Peptide |
|||
| AF8470-BP | Affbiotech | 1mg | EUR 234 |
Phospho-DRP1 (Ser616) Blocking Peptide |
|||
| DF2972-BP | Affbiotech | 1mg | EUR 234 |
Monoclonal Phospho-IRS (Ser616) Antibody (Clone HIR-B1), Clone: HIR-B1 |
|||
| APR09169G | Leading Biology | 0.1mg | EUR 580.8 |
|
Description: A Monoclonal antibody against Human Phospho-IRS (Ser616) (Clone HIR-B1). The antibodies are raised in Mouse and are from clone HIR-B1. This antibody is applicable in WB, E |
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Phospho-IRS-1 (Ser616) Blocking Peptide |
|||
| AF4423-BP | Affbiotech | 1mg | EUR 234 |
Phospho-Kv4.2/KCND2 (Ser616) Blocking Peptide |
|||
| AF8074-BP | Affbiotech | 1mg | EUR 234 |
IRS-1 (phospho Ser636) Rabbit pAb |
|||
| E2251484 | EnoGene | 100ul | EUR 225 |
|
Description: Available in various conjugation types. |
|||
Rat Phospho-IRS1 (Ser307) (p-IRS1 Ser307) ELISA kit |
|||
| YLA1466RA-48T | Shanghai YL Biotech | 48T | EUR 465 |
Rat Phospho-IRS1 (Ser307) (p-IRS1 Ser307) ELISA kit |
|||
| YLA1466RA-96T | Shanghai YL Biotech | 96T | EUR 600 |
Phospho-IRS1 (Ser639) Rabbit pAb |
|||
| E2341420 | EnoGene | 100μl | EUR 225 |
|
Description: Available in various conjugation types. |
|||
Rabbit Anti-Human IRS1 Polyclonal Antibody, Phospho-Ser636 |
|||
| CPB-768RH | Creative Diagnostics | 100 ul | EUR 670.8 |
Rabbit Anti-Human IRS1 Polyclonal Antibody, Phospho-Ser639 |
|||
| CPB-769RH | Creative Diagnostics | 100 ul | EUR 670.8 |
Rabbit Anti-Human IRS1 Polyclonal Antibody, Phospho-Ser312 |
|||
| CPB-1258RH | Creative Diagnostics | 100 ul | EUR 670.8 |
Rat Phospho-IRS1 (Ser307) ELISA Kit |
|||
| SL1309Ra | Sunlong | - | EUR 498 |
DRP1 (Phospho-Ser616) Antibody |
|||
| 12749-100ul | SAB | 100ul | EUR 302.4 |
DRP1 (Phospho-Ser616) Antibody |
|||
| 12749-50ul | SAB | 50ul | EUR 224.4 |
Insulin Receptor Substrate 1 Phospho-Ser307 (IRS1 pS307) Antibody |
|||
| abx333099-100ul | Abbexa | 100 ul | EUR 560.4 |
Insulin Receptor Substrate 1 Phospho-Ser636 (IRS1 pS636) Antibody |
|||
| abx333262-100ul | Abbexa | 100 ul | EUR 560.4 |
Insulin Receptor Substrate 1 Phospho-Ser639 (IRS1 pS639) Antibody |
|||
| abx333263-100ul | Abbexa | 100 ul | EUR 560.4 |
Insulin Receptor Substrate 1 Phospho-Ser312 (IRS1 pS312) Antibody |
|||
| abx333371-100ul | Abbexa | 100 ul | EUR 560.4 |
Insulin Receptor Substrate 1 Phospho-Ser312 (IRS1 pS312) Antibody |
|||
| 20-abx328087 | Abbexa |
|
|
Insulin Receptor Substrate 1 Phospho-Ser639 (IRS1 pS639) Antibody |
|||
| 20-abx328500 | Abbexa |
|
|
Insulin Receptor Substrate 1 Phospho-Ser307 (IRS1 pS307) Antibody |
|||
| 20-abx329188 | Abbexa |
|
|
Insulin Receptor Substrate 1 Phospho-Ser636 (IRS1 pS636) Antibody |
|||
| 20-abx329323 | Abbexa |
|
|
Insulin Receptor Substrate 1 Phospho-Ser794 (IRS1 pS794) Antibody |
|||
| 20-abx329494 | Abbexa |
|
|
Insulin Receptor Substrate 1 Phospho-Ser307 (IRS1 pS307) Antibody |
|||
| 20-abx330008 | Abbexa |
|
|
Insulin Receptor Substrate 1 Phospho-Ser323 (IRS1 pS323) Antibody |
|||
| 20-abx330033 | Abbexa |
|
|
Insulin Receptor Substrate 1 Phospho-Ser1101 (IRS1 pS1101) Antibody |
|||
| 20-abx329951 | Abbexa |
|
|
ATM (Phospho- Ser1981) Antibody |
|||
| ABF4120 | Lifescience Market | 100 ug | EUR 525.6 |
ATM (Phospho- Ser1981) Antibody |
|||
| ABF8225 | Lifescience Market | 100 ug | EUR 525.6 |
ATM (Phospho- Ser1981) Antibody |
|||
| ABF8409 | Lifescience Market | 100 ug | EUR 525.6 |
ATM (Phospho- Ser1987) Antibody |
|||
| ABF8410 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- GR (Ser203) Antibody |
|||
| ABF0042 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- GR (Ser211) Antibody |
|||
| ABF2004 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- GR (Ser226) Antibody |
|||
| ABF3066 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- GR (Ser203) Antibody |
|||
| ABF3067 | Lifescience Market | 100 ug | EUR 525.6 |
Phospho- Rb (Ser608) Antibody |
|||
| ABF3726 | Lifescience Market | 100 ug | EUR 525.6 |
Rb (Phospho- Ser795) Antibody |
|||
| E11-7209A | EnoGene | 100μg/100μl | EUR 225 |
|
Description: Available in various conjugation types. |
|||
eNOS (Phospho- Ser1179) Antibody |
|||
| ABF8086 | Lifescience Market | 100 ug | EUR 525.6 |
TIE2 (Phospho- Ser1119) Antibody |
|||
| ABF8193 | Lifescience Market | 100 ug | EUR 525.6 |
CD91 (Phospho- Ser4520) Antibody |
|||
| ABF8207 | Lifescience Market | 100 ug | EUR 525.6 |
nNOS (Phospho- Ser1417) Antibody |
|||
| ABF8231 | Lifescience Market | 100 ug | EUR 525.6 |
MUC1 (Phospho- Ser1227) Antibody |
|||
| ABF8289 | Lifescience Market | 100 ug | EUR 525.6 |
LRP6 (Phospho- Ser1490) Antibody |
|||
| ABF8344 | Lifescience Market | 100 ug | EUR 525.6 |
TSC2 (Phospho- Ser1254) Antibody |
|||
| ABF8354 | Lifescience Market | 100 ug | EUR 525.6 |
HSL (Phospho- Ser660) Antibody |
|||
| ABF8026 | Lifescience Market | 100 ug | EUR 525.6 |
ATM (Phospho- Ser367) Antibody |
|||
| ABF8099 | Lifescience Market | 100 ug | EUR 525.6 |
ATM (Phospho- Ser183) Antibody |
|||
| ABF8100 | Lifescience Market | 100 ug | EUR 525.6 |
Met (Phospho- Ser985) Antibody |
|||
| ABF8121 | Lifescience Market | 100 ug | EUR 525.6 |
KIT (Phospho- Ser746) Antibody |
|||
| ABF8162 | Lifescience Market | 100 ug | EUR 525.6 |
ZAK (Phospho- Ser165) Antibody |
|||
| ABF8195 | Lifescience Market | 100 ug | EUR 525.6 |
FAK (Phospho- Ser732) Antibody |
|||
| ABF8227 | Lifescience Market | 100 ug | EUR 525.6 |
Fos (Phospho- Ser374) Antibody |
|||
| ABF8270 | Lifescience Market | 100 ug | EUR 525.6 |
A 5′-deletion study showed that the promoter can be truncated to 600 bp long relative to the translation start site without affecting expression. A positive regulatory element was identified between 600 and 481 bp that controls expression in the inner integument, with no noticeable effect on expression in the outer integument or tapetum. Additionally, removal of the 5’UTR intron had no effect on levels or location of gm-hir1 expression while truncation to 370 bp resulted in a complete loss of expression suggesting that elements controlling both the outer integument and tapetum expression are located within the 481-370 bp region.